News

 
Congrats to superstar grad student Joshi Frenster for successfully defending his thesis on August 31 2020!

Congrats to superstar grad student Joshi Frenster for successfully defending his thesis on August 31 2020!

A warm welcome to Jordan Wilcox, who joined the lab as our technician on August 31 2020. Welcome Jordan! We are thrilled to have you join the group.

Congrats to Niklas Boess, super talented grad student in the lab, for earning a spot on the T32 Cell Biology training grant at NYU School of Medicine! Keep up the good work Niklas!

Congrats to Niklas Boess, super talented grad student in the lab, for earning a spot on the T32 Cell Biology training grant at NYU School of Medicine! Keep up the good work Niklas!

 

Congrats to our super talented MSTP student Devin Bready for his NCI F31 predoctoral fellowship! Proud of you, Devin!

Lab outing as we recover from the COVID pandemic. We survived it, carried each other through the hardship, and are emrging stronger!

Lab outing as we recover from the COVID pandemic. We survived it, carried each other through the hardship, and are emerging stronger!

Congrats again to Niklas Boess for the competitive renewal of his NYSTEM Training Grant spot! Proud of you Niklas!

Congrats again to Niklas Boess for earning a spot on the NYSTEM (New York State) Stem Cell Biology Training Program at NYU Grossman School of Medicine! Proud of you Niklas!

Congrats to our superstar NYU undergraduate student Rebecca Ronnen for being awarded a DURF fellowship from NYU!

A warm welcome to our new postdoc, Sara Haddock! We are excited to have you join the team!

Congrats to Dr. Niklas Boess in our group (recent PhD graduate) on his beautiful Cell Reports paper on CD97, an adhesion GPCR, in GBM! Great mechanistic insights and a terrific translational aspect. Niklas showed that: 1) CD97 is an adhesion GPCR that is de novo expressed in GBM compared to healthy brain; 2) CD97 promotes tumorigenesis and glycolytic metabolism in GBM via MAPK signaling; 3) Phosphorylation of the C terminus of CD97 leads to β-arrestin recruitment; and 4) GBM cells can be selectively killed using a CD97-targeting antibody-drug conjugate.

This work was based on a great collaboration with our NYU colleagues Shohei Koide and Chris Park. Many thanks to the Aifantis and Neel groups for reagents, the core facilities at NYU, and our patients.

https://doi.org/10.1016/j.celrep.2023.113374

Congrats to Dr. Niklas Boess for successfully defending his PhD thesis! Amazing job Niklas!

We are sad to say goodbye to our lab manager Jonathan Sabio, who is leaving our group for a new and exciting position. Thank you for everything you’ve done for the lab Jonathan! Best of luck in the new position! We will miss your kindness and humor.

Congrats to Sumru Bayin, the very first grad student in our lab, who will soon be starting her own lab at Gurdon Institute in Cambridge. So proud of you Sumru! You are amazing!

Congrats to Joshi Frenster, who is starting a postdoc with Alfonso Martinez Arias in Barcelona next month. Joshi has been an incredible grad student and postdoc in the lab; an amazing scientist, leader and mentor; and a good friend to all of us. He will be missed. We’re grateful for everything he has done for our group and so proud of him! See you soon, Joshi! We will miss you!

We are excited to welcome our new postdoctoral fellow, Shuai Wang, MD, PhD, to the lab!

We bid goodbye to our amazing postdoc Gabi Stephan. Gabi did some pioneering work on adhesion GPCRs in our lab, and wrote several manuscripts (the most recent in review). Good luck Gabi! Keep making us proud!

Gabi Stephan’s last lab meeting. We will miss you Gabi!

Congrats to Joshi Frenster on his manuscript “PTK7 is a positive allosteric modulator of GPR133 signaling in glioblastoma”, which just got published in Cell Reports. Joshi used affinity proteomics to identify PTK7 as a GPR133 ligand in GBM. PTK7 binding produces positive allosteric effects on GPR133 signaling when the two proteins interact in trans (on neighboring cells). This mechanism may be relevant to the pathogenesis of GBM and other malignancies. Thank you for your amazing work, Joshi!

https://doi.org/10.1016/j.celrep.2023.112679

Congrats to Rebecca Ronnen, our brilliant NYU undergrad, for being awarded DURF award, and being named a Salant Family Research Scholar and nominee for the Goldwater Scholarship! Proud of you Rebecca!

Congratulations to lab alum Aram Modrek, MD, PhD, who just opened his lab at USC! Aram is a physician-scientist in Radiation Oncology, and will study genome integrity and organization in glioblastoma. He is one of the smartest people I know and I am sure he will make very important contributions to the field. So proud of you Aram!

Congrats to Adler Guerrero, who just graduated from NYU with Honors, and is moving to Johns Hopkins for graduate school. Adler was salutatorian at NYU and received numerous awards for his academic excellence. Proud of you Adler!

Congrats to Adler Guerrero, who just graduated from NYU with Honors, and is moving to Johns Hopkins for graduate school. Adler was salutatorian at NYU and received numerous awards for his academic excellence. Proud of you Adler!

Congrats to our superstar NYU undergraduate student Julia Cai for being awarded a DURF fellowship from NYU!

Congrats to lab alumnus Aram Modrek, MD, PhD, for starting his career as physician-scientist in Radiation Oncology at USC this summer (2023)! Super proud of you, Aram!

Exciting news! So happy for our beloved postdoc Gabi Stephan, who just gave birth to a healthy, handsome baby boy, Luca. Congrats, Gabi, Ivan and Luca!

Congrats to our beloved MSTP student Devin Bready on his nuptials! We wish you and Morgan a lifetime of love, happiness and health!

Congratulations to Jonathan Sabio for his nuptials! We wish you and Martina a lifetime of love, happiness and health! Thank you for all you do in the lab, Jonathan.

Congrats to Hayley Donaldson on winning First Prize at the Northeast Medical Student Neurosurgery Research Symposium, for her work on anti-CD97 biologics in GBM. Proud of you Hayley!

Farewell dinner for Niklas Boess and Devin Bready who defended their PhD theses in August and September 2023. We are so proud of you and will miss you! We look forward to following your careers!

Congratulations to Dr. Devin Bready for successfully defending his PhD thesis! Incredible work Devin!

Congrats to Rebecca Ronnen, undergraduate student in the lab, who just won the Barry Goldwater Scholarship at NYU! Proud of you Rebecca!